The routine use of Sephadex to estimate "free" bilirubin and the residual serum bilirubin binding capacity.

Those of your readers who are interested in anticonvulsant-drug analyses will be familiar with the drugs ethotoin (Peganone#{174}, 3-ethyl-5-phenylhydantoin) and mephenytoin (Mesantoin#{174}, 5-ethyl-3methyl-5-phenylhydantoin). They will also be familiar with the name Nirvanol#{174}. Unfortunately, a dreadful state of confusion exists among various authorities as to whether Nirvanol is ethotoin or the N-demethylated metabolite of mephenytoin: 5-ethyl-5-phenylhydantoin. I suggest the easiest solution is to completelydrop the term Nirvanol from our vocabulary.